We are a mixed computational/experimental group located in the School of Biomedical Engineering at the University of British Columbia in Vancouver, Canada. We study gene regulation.
Although each cell in your body has the same genome sequence, they are all doing different things. Cell types can carry out distinct functions by expressing different sets of genes. The regulatory program that dictates when and where a gene should be expressed is encoded in the DNA. When a gene is expressed at the wrong place or time, disease can result. We seek to understand the logic of gene regulation so that we can correct misregulation in disease, understand its evolution, and engineer novel regulatory functions. Read more…
